{"id":14,"date":"2016-04-05T21:59:11","date_gmt":"2016-04-05T21:59:11","guid":{"rendered":"http:\/\/projects.nib.si\/itfcart\/?page_id=14"},"modified":"2022-04-05T18:47:24","modified_gmt":"2022-04-05T17:47:24","slug":"summary","status":"publish","type":"page","link":"https:\/\/projects.nib.si\/iTFCarT\/summary\/","title":{"rendered":"Project overview"},"content":{"rendered":"<p>The overarching goal of the project is to develop CAR T cells genetically equipped for improved expansion, persistence, and anti-tumor function. We will achieve this by the genetic integration of transcription factors (TFs) into CAR T cells. In addition, we will explore the mechanisms by which TFs can improve the therapeutic efficacy of CAR T cells, and with this new understanding of T cell biology, lay the foundations for the development of more effective cellular immunotherapies for cancer. Please see section \u201c<a title=\"Permalink to Project phases and realisation\" href=\"http:\/\/projects.nib.si\/iTFCarT\/project-phases-and-realisation\/\" rel=\"bookmark\">Project phases and realisation<\/a>\u201d for more information.<\/p>\n<p>We are open for collaborations, if you&#8217;re interested please contact <a href=\"http:\/\/Anze.Smole@nib.si\">dr An\u017ee Smole<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The overarching goal of the project is to develop CAR T cells genetically equipped for improved expansion, persistence, and anti-tumor function. We will achieve this by the genetic integration of transcription factors (TFs) into CAR T cells. In addition, we will explore the mechanisms by which TFs can improve the therapeutic efficacy of CAR T [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"page-fullwidth.php","meta":{"footnotes":""},"class_list":["post-14","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P7OqMV-e","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/pages\/14","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/comments?post=14"}],"version-history":[{"count":25,"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/pages\/14\/revisions"}],"predecessor-version":[{"id":343,"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/pages\/14\/revisions\/343"}],"wp:attachment":[{"href":"https:\/\/projects.nib.si\/iTFCarT\/wp-json\/wp\/v2\/media?parent=14"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}