According to the objectives of the proposed project, the work programme is structured into 5 interdependent thematic work packages (WP, Figure 2A) with 11 tasks (each corresponds to a milestone).

WP1. Acquisition and setup of computational and data resources 

WP2. Development of gene expression models

WP3. Knowledge and data-driven metabolic modeling

WP4. Model interpretation and validation

WP5. Project management and dissemination